The vegetative state

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The vegetative state.

The vegetative state may develop suddenly (as a consequence of traumatic or non-traumatic brain injury, such as hypoxia or anoxia; infection; or haemorrhage) or gradually (in the course of a neurodegenerative disorder, such as Alzheimer’s disease). Although uncommon, the condition is perplexing because there is an apparent dissociation between the two cardinal elements of consciousness: awarene...

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Cognition in the vegetative state.

Awake but not aware: This puzzling dissociation of the two central elements of consciousness defines the vegetative state. Traditionally, this condition has been believed to imply a brain with preserved hypothalamic and brainstem autonomic functions but with no capacity for cortical cognitive processes. As is discussed in this review, over a 20-year span neuroimaging techniques have clearly dem...

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Limbic hyperconnectivity in the vegetative state.

OBJECTIVE To investigate functional connectivity between the default mode network (DMN) and other networks in disorders of consciousness. METHODS We analyzed MRI data from 11 patients in a vegetative state and 7 patients in a minimally conscious state along with age- and sex-matched healthy control subjects. MRI data analysis included nonlinear spatial normalization to compensate for disease-...

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Cortical function in the persistent vegetative state.

expressed quantitative cerebral activity is crucial. The strongest evidence that supports the concept of early recovery of awareness in Menon et al.'s patient is that she ultimately recovered consciousness. Had she never regained any additional expressed qualities of attention, recognition, or interactive behavior beyond the P300 and the PET findings after another eight months (i.e. a year afte...

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Covert cognition in the persistent vegetative state.

Brain damage can sometimes render a patient persistently unresponsive and yet apparently awake, admitting the possibility that the absence of overt voluntary behaviour might conceal a retained capacity for covert cognition. When given instructions to perform a cognitive task, a minority of patients in such a so-called persistent vegetative state (PVS) has recently been found to exhibit patterns...

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ژورنال

عنوان ژورنال: Journal of Neurology, Neurosurgery & Psychiatry

سال: 2002

ISSN: 0022-3050

DOI: 10.1136/jnnp.73.4.355